Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment

Upon entry into the host cell cytosol, the facultative intracellular pathogen Listeria monocytogenes coordinates the expression of numerous essential virulence factors by allosteric binding of glutathione (GSH) to the Crp-Fnr family transcriptional regulator PrfA. Here, we report that robust virulen...

Descripción completa

Detalles Bibliográficos
Autores principales: Portman, Jonathan L., Dubensky, Samuel B., Peterson, Bret N., Whiteley, Aaron T., Portnoy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646252/
https://www.ncbi.nlm.nih.gov/pubmed/29042499
http://dx.doi.org/10.1128/mBio.01595-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646252/
https://www.ncbi.nlm.nih.gov/pubmed/29042499
http://dx.doi.org/10.1128/mBio.01595-17

Ejemplares similares