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Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment
Upon entry into the host cell cytosol, the facultative intracellular pathogen Listeria monocytogenes coordinates the expression of numerous essential virulence factors by allosteric binding of glutathione (GSH) to the Crp-Fnr family transcriptional regulator PrfA. Here, we report that robust virulen...
Autores principales: | Portman, Jonathan L., Dubensky, Samuel B., Peterson, Bret N., Whiteley, Aaron T., Portnoy, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646252/ https://www.ncbi.nlm.nih.gov/pubmed/29042499 http://dx.doi.org/10.1128/mBio.01595-17 |
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