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Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers

The development of foldamers capable of selective molecular recognition of solvent exposed protein surfaces represents an outstanding challenge in supramolecular chemical biology. Here we introduce an oligoamide foldamer with well-defined conformation that bears all the hallmarks of an information r...

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Detalles Bibliográficos
Autores principales: Azzarito, Valeria, Miles, Jennifer A., Fisher, Julie, Edwards, Thomas A., Warriner, Stuart L., Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646261/
https://www.ncbi.nlm.nih.gov/pubmed/29308155
http://dx.doi.org/10.1039/c4sc03559c