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Mechanism of Mechanical Trauma-Induced Extracellular Matrix Remodeling of Fibroblasts in Association with Nrf2/ARE Signaling Suppression Mediating TGF-β1/Smad3 Signaling Inhibition

Stress urinary incontinence (SUI) is a common hygienic problem affecting the quality of women's life worldwide. In this research, we revealed the involvement and regulation of extracellular matrix (ECM) remodeling, oxidative damage, and TGF-β1 signaling in the pathological mechanisms of mechani...

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Detalles Bibliográficos
Autores principales: Tang, Jianming, Li, Bingshu, Liu, Cheng, Li, Yang, Li, Qiannan, Wang, Linlin, Min, Jie, Hu, Ming, Hong, Shasha, Hong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646330/
https://www.ncbi.nlm.nih.gov/pubmed/29109834
http://dx.doi.org/10.1155/2017/8524353