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Rates of hippocampal atrophy and post-mortem TDP-43 in Alzheimer’s disease: a longitudinal retrospective study

BACKGROUND: Post-mortem studies have not identified an association between beta-amyloid or tau and rates of hippocampal atrophy in Alzheimer’s disease. TAR DNA binding protein of 43kDa (TDP-43) is another protein recently linked to Alzheimer’s disease. We aimed to determine whether hippocampal TDP-4...

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Detalles Bibliográficos
Autores principales: Josephs, Keith A., Dickson, Dennis W., Tosakulwong, Nirubol, Weigand, Stephen D., Murray, Melissa E., Petrucelli, Leonard, Liesinger, Amanda M., Senjem, Matthew L., Spychalla, Anthony J., Knopman, David S., Parisi, Joseph E., Petersen, Ronald C., Jack, Clifford R., Whitwell, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646369/
https://www.ncbi.nlm.nih.gov/pubmed/28919059
http://dx.doi.org/10.1016/S1474-4422(17)30284-3