The Natural Flavone Acacetin Blocks Small Conductance Ca(2+)-Activated K(+) Channels Stably Expressed in HEK 293 Cells

The natural flavone acacetin inhibits several voltage-gated potassium currents in atrial myocytes, and has anti-atrial fibrillation (AF) effect in experimental AF models. The present study investigates whether acacetin inhibits the Ca(2+)-activated potassium (K(Ca)) currents, including small conduct...

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Detalles Bibliográficos
Autores principales: Chen, Kui-Hao, Liu, Hui, Sun, Hai-Ying, Jin, Man-Wen, Xiao, Guo-Sheng, Wang, Yan, Li, Gui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646423/
https://www.ncbi.nlm.nih.gov/pubmed/29081746
http://dx.doi.org/10.3389/fphar.2017.00716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646423/
https://www.ncbi.nlm.nih.gov/pubmed/29081746
http://dx.doi.org/10.3389/fphar.2017.00716

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