Gadolinium and Platinum in Tandem: Real-time Multi-Modal Monitoring of Drug Delivery by MRI and Fluorescence Imaging

A novel dual-imaging cisplatin-carrying molecular cargo capable of performing simultaneous optical and MR imaging is reported herein. This long-lasting MRI contrast agent (r(1) relaxivity of 23.4 mM(-1)s(-1) at 3T, 25 (o)C) is a photo-activated cisplatin prodrug (PtGdL) which enables real-time monit...

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Detalles Bibliográficos
Autores principales: Li, Hongguang, Harriss, Bethany I., Phinikaridou, Alkystis, Lacerda, Sara, Ramniceanu, Gregory, Doan, Bich-Thuy, Ho, Ka-Lok, Chan, Chi-Fai, Lo, Wai-Sum, Botnar, René M., Lan, Rongfeng, Richard, Cyrille, Law, Ga-Lai, Long, Nicholas J., Wong, Ka-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646715/
https://www.ncbi.nlm.nih.gov/pubmed/29071187
http://dx.doi.org/10.7150/ntno.18619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646715/
https://www.ncbi.nlm.nih.gov/pubmed/29071187
http://dx.doi.org/10.7150/ntno.18619

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