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Protective effect of low-dose risedronate against osteocyte apoptosis and bone loss in ovariectomized rats

Osteocyte apoptosis is the first reaction to estrogen depletion, thereby stimulating osteoclastic bone resorption resulting in bone loss. We investigated the effects of two different risedronate (RIS) doses (high and low) on osteocyte apoptosis, osteoclast activity and bone loss in ovariectomized ra...

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Detalles Bibliográficos
Autores principales: Ye, Tingjun, Cao, Peng, Qi, Jin, Zhou, Qi, Rao, D. Sudhaker, Qiu, Shijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646759/
https://www.ncbi.nlm.nih.gov/pubmed/29045447
http://dx.doi.org/10.1371/journal.pone.0186012