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Protective effect of low-dose risedronate against osteocyte apoptosis and bone loss in ovariectomized rats
Osteocyte apoptosis is the first reaction to estrogen depletion, thereby stimulating osteoclastic bone resorption resulting in bone loss. We investigated the effects of two different risedronate (RIS) doses (high and low) on osteocyte apoptosis, osteoclast activity and bone loss in ovariectomized ra...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646759/ https://www.ncbi.nlm.nih.gov/pubmed/29045447 http://dx.doi.org/10.1371/journal.pone.0186012 |