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Conjugated nanoliposome with the HER2/neu-derived peptide GP2 as an effective vaccine against breast cancer in mice xenograft model

One of the challenging issues in vaccine development is peptide and adjuvant delivery into target cells. In this study, we developed a vaccine and therapeutic delivery system to increase cytotoxic T lymphocyte (CTL) response against a breast cancer model overexpressing HER2/neu. Gp2, a HER2/neu-deri...

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Detalles Bibliográficos
Autores principales: Razazan, Atefeh, Behravan, Javad, Arab, Atefeh, Barati, Nastaran, Arabi, Leila, Gholizadeh, Zahra, Hatamipour, Mahdi, Reza Nikpoor, Amin, Momtazi-Borojeni, Amir Abbas, Mosaffa, Fatemeh, Ghahremani, Mohamad Hosein, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646774/
https://www.ncbi.nlm.nih.gov/pubmed/29045460
http://dx.doi.org/10.1371/journal.pone.0185099