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Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation

The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complications and adverse fetal outcomes and program the fetus for obesity and metabolic syndrome in later life. We hypothesized that epigenetic modifications in...

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Detalles Bibliográficos
Autores principales: Mitsuya, Kohzoh, Parker, Ashley N., Liu, Lu, Ruan, Jianhua, Vissers, Margreet C. M., Myatt, Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646778/
https://www.ncbi.nlm.nih.gov/pubmed/29045485
http://dx.doi.org/10.1371/journal.pone.0186115