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Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation
The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complications and adverse fetal outcomes and program the fetus for obesity and metabolic syndrome in later life. We hypothesized that epigenetic modifications in...
Autores principales: | Mitsuya, Kohzoh, Parker, Ashley N., Liu, Lu, Ruan, Jianhua, Vissers, Margreet C. M., Myatt, Leslie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646778/ https://www.ncbi.nlm.nih.gov/pubmed/29045485 http://dx.doi.org/10.1371/journal.pone.0186115 |
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