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Contribution of proton leak to oxygen consumption in skeletal muscle during intense exercise is very low despite large contribution at rest
A computer model was used to simulate the dependence of protonmotive force (Δp), proton leak and phenomenological (involving proton leak) ATP/O(2) ratio on work intensity in skeletal muscle. Δp, NADH and proton leak decreased with work intensity. The contribution of proton leak to oxygen consumption...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646787/ https://www.ncbi.nlm.nih.gov/pubmed/29045413 http://dx.doi.org/10.1371/journal.pone.0185991 |