Inhibition of apoptosis signal-regulating kinase 1 alters the wound epidermis and enhances auricular cartilage regeneration

Why regeneration does not occur in mammals remains elusive. In lower vertebrates, epimorphic regeneration of the limb is directed by the wound epidermis, which controls blastema formation to promote regrowth of the appendage. Herein, we report that knockout (KO) or inhibition of Apoptosis Signal-reg...

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Detalles Bibliográficos
Autores principales: Zhang, Qian-Shi, Kurpad, Deepa S., Mahoney, My G., Steinbeck, Marla J., Freeman, Theresa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646791/
https://www.ncbi.nlm.nih.gov/pubmed/29045420
http://dx.doi.org/10.1371/journal.pone.0185803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646791/
https://www.ncbi.nlm.nih.gov/pubmed/29045420
http://dx.doi.org/10.1371/journal.pone.0185803

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