A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence

A feature of mature Plasmodium falciparum parasitized red blood cells is their ability to bind surface molecules of the microvascular endothelium via the parasite-derived surface protein Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). This ligand is associated with the cytoadherence p...

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Detalles Bibliográficos
Autores principales: Skidmore, Mark A., Mustaffa, Khairul Mohd Fadzli, Cooper, Lynsay C., Guimond, Scott E., Yates, Edwin A., Craig, Alister G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646806/
https://www.ncbi.nlm.nih.gov/pubmed/29045442
http://dx.doi.org/10.1371/journal.pone.0186276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646806/
https://www.ncbi.nlm.nih.gov/pubmed/29045442
http://dx.doi.org/10.1371/journal.pone.0186276

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