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A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence

A feature of mature Plasmodium falciparum parasitized red blood cells is their ability to bind surface molecules of the microvascular endothelium via the parasite-derived surface protein Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). This ligand is associated with the cytoadherence p...

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Detalles Bibliográficos
Autores principales:	Skidmore, Mark A., Mustaffa, Khairul Mohd Fadzli, Cooper, Lynsay C., Guimond, Scott E., Yates, Edwin A., Craig, Alister G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646806/ https://www.ncbi.nlm.nih.gov/pubmed/29045442 http://dx.doi.org/10.1371/journal.pone.0186276

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