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Novel drug targets in cell wall biosynthesis exploited by gene disruption in Pseudomonas aeruginosa

For clinicians, Pseudomonas aeruginosa is a nightmare pathogen that is one of the top three causes of opportunistic human infections. Therapy of P. aeruginosa infections is complicated due to its natural high intrinsic resistance to antibiotics. Active efflux and decreased uptake of drugs due to cel...

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Detalles Bibliográficos
Autores principales: Elamin, Ayssar A., Steinicke, Susanne, Oehlmann, Wulf, Braun, Yvonne, Wanas, Hanaa, Shuralev, Eduard A., Huck, Carmen, Maringer, Marko, Rohde, Manfred, Singh, Mahavir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646862/
https://www.ncbi.nlm.nih.gov/pubmed/29045498
http://dx.doi.org/10.1371/journal.pone.0186801