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The ins and outs of vanillyl alcohol oxidase: Identification of ligand migration paths

Vanillyl alcohol oxidase (VAO) is a homo-octameric flavoenzyme belonging to the VAO/PCMH family. Each VAO subunit consists of two domains, the FAD-binding and the cap domain. VAO catalyses, among other reactions, the two-step conversion of p-creosol (2-methoxy-4-methylphenol) to vanillin (4-hydroxy-...

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Detalles Bibliográficos
Autores principales: Gygli, Gudrun, Lucas, Maria Fátima, Guallar, Victor, van Berkel, Willem J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646868/
https://www.ncbi.nlm.nih.gov/pubmed/28985219
http://dx.doi.org/10.1371/journal.pcbi.1005787