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Co-expression of Axin and APC gene fragments inhibits colorectal cancer cell growth via regulation of the Wnt signaling pathway

Adenomatous polyposis coli (APC) and Axin interactions serve an important role in colorectal cancer (CRC) pathogenesis. The aim of the present study was to assess the combined effects of Axin and APC co-expression in CRC cells, and to determine the underlying mechanisms involved. SW480 cells were di...

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Detalles Bibliográficos
Autores principales: Xu, Meili, Liu, Xianling, Xu, Yan, Zhu, Shicong, Gao, Yawen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646956/
https://www.ncbi.nlm.nih.gov/pubmed/28731177
http://dx.doi.org/10.3892/mmr.2017.7049