Anti-CD20 monoclonal antibody combined with adenovirus vector-mediated IL-10 regulates spleen CD4(+)/CD8(+) T cells and T-bet/GATA-3 expression in NOD mice

Type 1 diabetes (T1D) is an autoimmune disease characterized by a selective destruction of insulin-secreting β-cells. Both T cells and B cells serve a crucial role in pathogenesis and development of T1D. CD20 is a specific membrane antigen of B lymphocytes, while interleukin (IL)-10 is an important...

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Detalles Bibliográficos
Autores principales: Tang, Aiping, Li, Cheng, Chen, Zhihong, Li, Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646977/
https://www.ncbi.nlm.nih.gov/pubmed/28765956
http://dx.doi.org/10.3892/mmr.2017.7111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646977/
https://www.ncbi.nlm.nih.gov/pubmed/28765956
http://dx.doi.org/10.3892/mmr.2017.7111

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