Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling

Previous studies have demonstrated that lercanidipine, a calcium channel blocker, may protect against cardiac hypertrophy; however, the underlying mechanisms remain unclear. In the present study, the effects of lercanidipine on hypertrophy and the mechanisms involved were investigated. Cardiomyocyte...

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Detalles Bibliográficos
Autores principales: Chen, Yuezhang, Yuan, Jie, Jiang, Guoliang, Zhu, Jianbing, Zou, Yunzeng, Lv, Qianzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646991/
https://www.ncbi.nlm.nih.gov/pubmed/28849081
http://dx.doi.org/10.3892/mmr.2017.7211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646991/
https://www.ncbi.nlm.nih.gov/pubmed/28849081
http://dx.doi.org/10.3892/mmr.2017.7211

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