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Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling
Previous studies have demonstrated that lercanidipine, a calcium channel blocker, may protect against cardiac hypertrophy; however, the underlying mechanisms remain unclear. In the present study, the effects of lercanidipine on hypertrophy and the mechanisms involved were investigated. Cardiomyocyte...
Autores principales: | Chen, Yuezhang, Yuan, Jie, Jiang, Guoliang, Zhu, Jianbing, Zou, Yunzeng, Lv, Qianzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646991/ https://www.ncbi.nlm.nih.gov/pubmed/28849081 http://dx.doi.org/10.3892/mmr.2017.7211 |
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