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Molecular dynamics simulations of human E3 ubiquitin ligase Parkin

Human E3 ubiquitin protein ligase parkin (Parkin) mediates mitophagy to maintain mitochondrial homeostasis. Parkin mutations are common genetic causes of early onset familial Parkinson's disease. The molecular mechanism of Parkin activation has been widely studied with emerging evidence suggest...

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Detalles Bibliográficos
Autores principales: Qiu, Shi, Zhu, Shun, Xu, Shan, Han, Yanyan, Liu, Wen, Zuo, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646993/
https://www.ncbi.nlm.nih.gov/pubmed/28765939
http://dx.doi.org/10.3892/mmr.2017.7140