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PCDH9 acts as a tumor suppressor inducing tumor cell arrest at G(0)/G(1) phase and is frequently methylated in hepatocellular carcinoma

Tumor suppressor genes (TSGs) are frequently involved in the pathogenesis of hepatocellular carcinoma (HCC). The epigenetic and genetic alterations of a novel TSG-protocadherin 9 (PCDH9) and its functions in the pathogenesis of HCC were investigated. The methylation status of the PCDH9 promoter was...

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Detalles Bibliográficos
Autores principales: Lv, Jun, Zhu, Pengfei, Zhang, Xiaolei, Zhang, Ling, Chen, Xiangmei, Lu, Fengmin, Yu, Zujiang, Liu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647006/
https://www.ncbi.nlm.nih.gov/pubmed/28791409
http://dx.doi.org/10.3892/mmr.2017.7193