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PCDH9 acts as a tumor suppressor inducing tumor cell arrest at G(0)/G(1) phase and is frequently methylated in hepatocellular carcinoma
Tumor suppressor genes (TSGs) are frequently involved in the pathogenesis of hepatocellular carcinoma (HCC). The epigenetic and genetic alterations of a novel TSG-protocadherin 9 (PCDH9) and its functions in the pathogenesis of HCC were investigated. The methylation status of the PCDH9 promoter was...
Autores principales: | Lv, Jun, Zhu, Pengfei, Zhang, Xiaolei, Zhang, Ling, Chen, Xiangmei, Lu, Fengmin, Yu, Zujiang, Liu, Shuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647006/ https://www.ncbi.nlm.nih.gov/pubmed/28791409 http://dx.doi.org/10.3892/mmr.2017.7193 |
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