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A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis

The aim of the current study was to investigate the role and mechanism of sirtuin 1 (Sirt1) in the regulation of synovial cell invasion and joint destruction in rheumatoid arthritis (RA). The Sirt1 protein and mRNA levels in fibroblast-like synoviocytes (FLS) isolated from RA synovial tissues were c...

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Detalles Bibliográficos
Autores principales: Hao, Liang, Wan, Yuying, Xiao, Juhua, Tang, Qiang, Deng, Huan, Chen, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647035/
https://www.ncbi.nlm.nih.gov/pubmed/28849139
http://dx.doi.org/10.3892/mmr.2017.7299