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Methylation of mitochondrial DNA displacement loop region regulates mitochondrial copy number in colorectal cancer

It is not established whether de-methylation of the displacement loop (D-loop) region if mitochondrial DNA (mtDNA) directly influences mtDNA copy number and further alters the cell cycle, apoptosis and cell proliferation in colorectal cancer. The current study employed cell viability assays, cell cy...

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Detalles Bibliográficos
Autores principales: Tong, Huan, Zhang, Linhao, Gao, Jinhang, Wen, Shilei, Zhou, Hongying, Feng, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647067/
https://www.ncbi.nlm.nih.gov/pubmed/28849075
http://dx.doi.org/10.3892/mmr.2017.7264