PML(NLS¯) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia

Promyelocyte leukemia-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Previous studies have reported that neutrophil elastase (NE) cleaves PML-RARα in early myeloid cells, which leads to the removal of the nuclear localization signal (NLS) in PML...

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Detalles Bibliográficos
Autores principales: Shan, Zhi-Ling, Zhu, Xin-Yu, Ma, Peng-Peng, Wang, Hui, Chen, Jianbin, Li, Jun, Zhong, Liang, Liu, Bei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647086/
https://www.ncbi.nlm.nih.gov/pubmed/28849126
http://dx.doi.org/10.3892/mmr.2017.7272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647086/
https://www.ncbi.nlm.nih.gov/pubmed/28849126
http://dx.doi.org/10.3892/mmr.2017.7272

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