Cargando…

PML(NLS¯) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia

Promyelocyte leukemia-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Previous studies have reported that neutrophil elastase (NE) cleaves PML-RARα in early myeloid cells, which leads to the removal of the nuclear localization signal (NLS) in PML...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shan, Zhi-Ling, Zhu, Xin-Yu, Ma, Peng-Peng, Wang, Hui, Chen, Jianbin, Li, Jun, Zhong, Liang, Liu, Bei-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647086/ https://www.ncbi.nlm.nih.gov/pubmed/28849126 http://dx.doi.org/10.3892/mmr.2017.7272

Ejemplares similares

PML(NLS(-)) Inhibits Cell Apoptosis and Promotes Proliferation in HL-60 Cells
por: Gao, Yuan-Mei, et al.
Publicado: (2013)

Acute promyelocytic leukemia, arsenic, and PML bodies
por: de Thé, Hugues, et al.
Publicado: (2012)

NLS-RARα is a novel transcriptional factor
por: Jiang, Kai-Ling, et al.
Publicado: (2017)

Educational Case: Acute Promyelocytic Leukemia With PML-RARA
por: Kunak, Rebecca L., et al.
Publicado: (2019)

Role of Promyelocytic Leukemia (Pml) Protein in Tumor Suppression
por: Rego, Eduardo M., et al.
Publicado: (2001)

Location of NLS-RARα protein in NB4 cell and nude mice
por: Wang, Hui, et al.
Publicado: (2017)

NLS-RARα modulates acute promyelocytic leukemia NB4 cell proliferation and differentiation via the PI3K/AKT pathway
por: Song, Hao, et al.
Publicado: (2016)

Promyelocytic Leukemia Protein (Pml) and Daxx Participate in a Novel Nuclear Pathway for Apoptosis
por: Zhong, Sue, et al.
Publicado: (2000)

Promyelocytic Leukemia Protein (PML) Controls Listeria monocytogenes Infection
por: Ribet, David, et al.
Publicado: (2017)

Overexpression of promyelocytic leukemia protein and alteration of PML nuclear bodies in early stage of hepatocarcinogenesis.
por: Yoon, G. S., et al.
Publicado: (2001)

Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation
por: Zhang, Li, et al.
Publicado: (2014)

Promyelocytic Leukemia (PML) gene regulation: implication towards curbing oncogenesis
por: Datta, Neerajana, et al.
Publicado: (2019)

Effects of arsenic on the topology and solubility of promyelocytic leukemia (PML)-nuclear bodies
por: Hirano, Seishiro, et al.
Publicado: (2022)

Chromosomal abnormality of acute promyelocytic leukemia other than PML-RARA: a case report of acute promyelocytic leukemia with del(5q)
por: Imataki, Osamu, et al.
Publicado: (2016)

Characterization of cryptic rearrangements, deletion, complex variants of PML, RARA in acute promyelocytic leukemia
por: Amare, Pratibha Kadam, et al.
Publicado: (2011)

Molecular Heterogeneity of the PML Gene Rearrangement in Acute Promyelocytic Leukemia: Prevalence and Clinical Significance
por: Fukutani, Hisashi, et al.
Publicado: (1993)

Promyelocytic Leukemia (Pml) Nuclear Bodies Are Protein Structures That Do Not Accumulate RNA
por: Boisvert, François-Michel, et al.
Publicado: (2000)

Targeting Promyelocytic Leukemia Protein: A Means to Regulating PML Nuclear Bodies
por: Reineke, Erin L., et al.
Publicado: (2009)

Case Report: Co-existence of a novel EXOC4‐TRHDE gene fusion with PML-RARA in acute promyelocytic leukemia
por: Liu, Xiaodong, et al.
Publicado: (2023)

Immunophenotypes and Immune Markers Associated with Acute Promyelocytic Leukemia Prognosis
por: Xu, Fang, et al.
Publicado: (2014)

Flow cytometric immunobead assay for fast and easy detection of PML–RARA fusion proteins for the diagnosis of acute promyelocytic leukemia
por: Dekking, E H A, et al.
Publicado: (2012)

HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse
por: Coltella, Nadia, et al.
Publicado: (2014)

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia
por: Albano, Francesco, et al.
Publicado: (2015)

External quality assessment for PML‐RARα detection in acute promyelocytic leukemia: Findings and summary
por: Wu, Qisheng, et al.
Publicado: (2019)

Cytogenetically cryptic PML::RARA fusion in acute promyelocytic leukemia: Testing strategies in the modern era
por: Karlin, Kirill, et al.
Publicado: (2022)

PML–LRIF1 interactions form a novel link between promyelocytic leukemia bodies and centromeres
por: Li, Junying, et al.
Publicado: (2023)

Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia
por: dos Santos, Guilherme Augusto, et al.
Publicado: (2013)

3C protease of enterovirus 71 cleaves promyelocytic leukemia protein and impairs PML-NBs production
por: Li, Zhuoran, et al.
Publicado: (2021)

Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as(2)O(3)-Induced Pml or Pml/Retinoic Acid Receptor α Degradation
por: Lallemand-Breitenbach, Valérie, et al.
Publicado: (2001)

Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML)
por: Milutinovic, Snezana, et al.
Publicado: (2016)

Promyelocytic Leukemia (PML) Protein Plays Important Roles in Regulating Cell Adhesion, Morphology, Proliferation and Migration
por: Tang, Mei Kuen, et al.
Publicado: (2013)

NLS-RARα Promotes Proliferation and Inhibits Differentiation in HL-60 Cells
por: Hu, Xiu-Xiu, et al.
Publicado: (2014)

Genome-wide functions of PML–RARα in acute promyelocytic leukaemia
por: Saeed, S, et al.
Publicado: (2011)

Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study
por: Neto, Walter Kleine, et al.
Publicado: (2010)

High-Risk Microgranular Acute Promyelocytic Leukemia with a Five-Way Complex Translocation Involving PML-RARA
por: Powers, Benjamin, et al.
Publicado: (2015)

Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia
por: Hattori, Hikaru, et al.
Publicado: (2018)

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single PML-RARA Fusion Gene
por: Liquori, Alessandro, et al.
Publicado: (2020)

PML/RARa Interferes with NRF2 Transcriptional Activity Increasing the Sensitivity to Ascorbate of Acute Promyelocytic Leukemia Cells
por: Banella, Cristina, et al.
Publicado: (2019)

Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells
por: Shao, Xuejing, et al.
Publicado: (2022)

PML‐RARα interferes with erythropoiesis by repressing LMO2 in acute promyelocytic leukaemia
por: Yang, Xianwen, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rvbi8neh8qodtdu5mh6daa9e2v