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Amyloid β-42 induces neuronal apoptosis by targeting mitochondria

Alzheimer's disease (AD), with a typical pathological hallmark of amyloid-beta (Aβ)-containing plaques and neurofibrillary tangles, is one of the most common types of chronic neurodegenerative diseases. Aβ oligomers serve a crucial role in the pathogenesis of AD, and lead to neuronal loss. Howe...

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Detalles Bibliográficos
Autores principales: Han, Xiao-Jian, Hu, Yang-Yang, Yang, Zhang-Jian, Jiang, Li-Ping, Shi, Sheng-Lan, Li, Ye-Ru, Guo, Miao-Yu, Wu, Hong-Li, Wan, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647099/
https://www.ncbi.nlm.nih.gov/pubmed/28849115
http://dx.doi.org/10.3892/mmr.2017.7203