Cargando…

Amyloid β-42 induces neuronal apoptosis by targeting mitochondria

Alzheimer's disease (AD), with a typical pathological hallmark of amyloid-beta (Aβ)-containing plaques and neurofibrillary tangles, is one of the most common types of chronic neurodegenerative diseases. Aβ oligomers serve a crucial role in the pathogenesis of AD, and lead to neuronal loss. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Xiao-Jian, Hu, Yang-Yang, Yang, Zhang-Jian, Jiang, Li-Ping, Shi, Sheng-Lan, Li, Ye-Ru, Guo, Miao-Yu, Wu, Hong-Li, Wan, Yu-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647099/ https://www.ncbi.nlm.nih.gov/pubmed/28849115 http://dx.doi.org/10.3892/mmr.2017.7203

Ejemplares similares

Effects and mechanism of amyloid β(1-42) on mitochondria in astrocytes
por: Yao, Yunyi, et al.
Publicado: (2018)

Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ(1–42)-induced degeneration
por: Xu, Dan, et al.
Publicado: (2021)

Effects of NADPH Oxidase Inhibitors and Mitochondria-Targeted Antioxidants on Amyloid β(1-42)-Induced Neuronal Deaths in Mouse Mixed Cortical Cultures
por: Hwang, Shinae, et al.
Publicado: (2018)

Interferon-γ increases neuronal death in response to amyloid-β(1-42)
por: Bate, Clive, et al.
Publicado: (2006)

Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria
por: Saraiva, Leonardo M., et al.
Publicado: (2010)

Facilitation of Gastrointestinal (GI) Tract Microbiome-Derived Lipopolysaccharide (LPS) Entry Into Human Neurons by Amyloid Beta-42 (Aβ42) Peptide
por: Lukiw, Walter J., et al.
Publicado: (2019)

Conjugated Quantum Dots Inhibit the Amyloid β (1–42) Fibrillation Process
por: Thakur, Garima, et al.
Publicado: (2011)

Treponema denticola Induces Neuronal Apoptosis by Promoting Amyloid-β Accumulation in Mice
por: Wu, Linrui, et al.
Publicado: (2022)

The Protective Effects of Zeaxanthin on Amyloid-β Peptide 1–42-Induced Impairment of Learning and Memory Ability in Rats
por: Li, Xiaoying, et al.
Publicado: (2022)

Mitochondria, Amyloid β, and Alzheimer's Disease
por: Readnower, Ryan D., et al.
Publicado: (2011)

Baicalin Attenuated Aβ(1-42)-Induced Apoptosis in SH-SY5Y Cells by Inhibiting the Ras-ERK Signaling Pathway
por: Song, Zhenyan, et al.
Publicado: (2022)

Neuroprotective effects of ZL006 in Aβ(1–42)-treated neuronal cells
por: Tao, Wen-Yuan, et al.
Publicado: (2020)

Alcohol Dehydrogenase 1B Suppresses β-Amyloid-Induced Neuron Apoptosis
por: Wang, Yaqi, et al.
Publicado: (2019)

Microarray Analysis on Human Neuroblastoma Cells Exposed to Aluminum, β(1–42)-Amyloid or the β(1–42)-Amyloid Aluminum Complex
por: Gatta, Valentina, et al.
Publicado: (2011)

Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation
por: Malmsten, Linn, et al.
Publicado: (2014)

Detection of Amyloid-β(1–42) Aggregation With a Nanostructured Electrochemical Sandwich Immunoassay Biosensor
por: Wang, Bing-Yu, et al.
Publicado: (2022)

Influence of denaturants on amyloid β42 aggregation kinetics
por: Weiffert, Tanja, et al.
Publicado: (2022)

Few-layer bismuth selenides exfoliated by hemin inhibit amyloid-β(1–42) fibril formation
por: Peng, Jian, et al.
Publicado: (2015)

Interaction of lobed kudzuvine root, rhizoma chuanxiong with both acetylcholinesterase and beta-amyloid (Aβ1-42)
por: Shuai, Li, et al.
Publicado: (2013)

Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells
por: Mitkevich, V A, et al.
Publicado: (2013)

Amyloid β 1-42 induces hypometabolism in human stem cell-derived neuron and astrocyte networks
por: Tarczyluk, Marta A, et al.
Publicado: (2015)

Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide
por: Cheung, Yuen-Ting, et al.
Publicado: (2011)

Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ(42)
por: An, Seong Soo A., et al.
Publicado: (2017)

New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit β-Amyloid42 Production and Phospho-Tau (Thr217)
por: Li, Sheng, et al.
Publicado: (2023)

NMDAR-dependent somatic potentiation of synaptic inputs is correlated with β amyloid-mediated neuronal hyperactivity
por: Bao, Yifei, et al.
Publicado: (2021)

Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses
por: Yu, Yang, et al.
Publicado: (2018)

Amyloid Fibril Formation of Arctic Amyloid-β 1–42 Peptide is Efficiently Inhibited by the BRICHOS Domain
por: Zhong, Xueying, et al.
Publicado: (2022)

Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation
por: Braun, Gabriel A., et al.
Publicado: (2022)

RRY Inhibits Amyloid-β(1–42) Peptide Aggregation and Neurotoxicity
por: Sun, Xicui, et al.
Publicado: (2021)

The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid β-Induced Apoptosis
por: Song, Lin, et al.
Publicado: (2019)

Stability of Plasma Amyloid-β 1–40, Amyloid-β 1–42, and Total Tau Protein over Repeated Freeze/Thaw Cycles
por: Liu, Huei-Chun, et al.
Publicado: (2020)

Key Residues for the Formation of Aβ42 Amyloid Fibrils
por: Hsu, Frederick, et al.
Publicado: (2018)

Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway
por: Marshall, Karen E., et al.
Publicado: (2020)

Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β(3-42) peptide
por: Cho, Illhwan, et al.
Publicado: (2023)

Inhibitory Effect of Lycopene on Amyloid-β-Induced Apoptosis in Neuronal Cells
por: Hwang, Sinwoo, et al.
Publicado: (2017)

Alteration in amyloid β42, phosphorylated tau protein, interleukin 6, and acetylcholine during diabetes-accelerated memory dysfunction in diabetic rats: correlation of amyloid β42 with changes in glucose metabolism
por: Zhou, You, et al.
Publicado: (2015)

Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo
por: Eckert, Anne, et al.
Publicado: (2010)

Remedying the Mitochondria to Cure Human Diseases by Natural Products
por: Mu, Jian-Kang, et al.
Publicado: (2020)

Recombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β
por: Wan, Hua-Li, et al.
Publicado: (2022)

Death-associated protein kinase 1 mediates Aβ42 aggregation-induced neuronal apoptosis and tau dysregulation in Alzheimer's disease
por: Zhang, Tao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_r5n2bu3hnlmp110u4fjnep0p79