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Accelerating metabolism and transmembrane cation flux by distorting red blood cells

Under static conditions, mammalian red blood cells (RBCs) require a continuous supply of energy, typically via glucose, to maintain their biconcave disc shape. Mechanical distortion, in a complementary way, should lead to increased energy demand that is manifest in accelerated glycolysis. The experi...

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Detalles Bibliográficos
Autores principales: Kuchel, Philip W., Shishmarev, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647125/
https://www.ncbi.nlm.nih.gov/pubmed/29057326
http://dx.doi.org/10.1126/sciadv.aao1016