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DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

The Tet-On/Off system for conditional transgene expression constitutes state-of-the-art technology to study gene function by facilitating inducible expression in a timed and reversible manner. Several studies documented the suitability and versatility of this system to trace lymphocyte fate and to c...

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Detalles Bibliográficos
Autores principales: Ottina, Eleonora, Peperzak, Victor, Schoeler, Katia, Carrington, Emma, Sgonc, Roswitha, Pellegrini, Marc, Preston, Simon, Herold, Marco J., Strasser, Andreas, Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647323/
https://www.ncbi.nlm.nih.gov/pubmed/29044097
http://dx.doi.org/10.1038/s41467-017-01022-4