OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs

Ectopic expression of lineage master regulators induces transdifferentiation. Whether cell fate transitions can be induced during various developmental stages has not been systemically examined. Here we discover that amongst different developmental stages, mouse embryonic stem cells (mESCs) are resi...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheinboim, Danna, Maza, Itay, Dror, Iris, Parikh, Shivang, Krupalnik, Vladislav, Bell, Rachel E., Zviran, Asaf, Suita, Yusuke, Hakim, Ofir, Mandel-Gutfreund, Yael, Khaled, Mehdi, Hanna, Jacob H., Levy, Carmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647326/
https://www.ncbi.nlm.nih.gov/pubmed/29044103
http://dx.doi.org/10.1038/s41467-017-01122-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647326/
https://www.ncbi.nlm.nih.gov/pubmed/29044103
http://dx.doi.org/10.1038/s41467-017-01122-1

Ejemplares similares