Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test

Evidence exists that chronic antidepressant therapy enhances CREB levels and activity. Nevertheless, the data are not conclusive, as previous analysis of transgenic mouse models has suggested that CREB inactivation in fact contributes to antidepressant-like behavior. The aim of this study was to eva...

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Detalles Bibliográficos
Autores principales: Rafa–Zabłocka, Katarzyna, Kreiner, Grzegorz, Bagińska, Monika, Kuśmierczyk, Justyna, Parlato, Rosanna, Nalepa, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647346/
https://www.ncbi.nlm.nih.gov/pubmed/29044198
http://dx.doi.org/10.1038/s41598-017-14069-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647346/
https://www.ncbi.nlm.nih.gov/pubmed/29044198
http://dx.doi.org/10.1038/s41598-017-14069-6

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