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A Machine Learning Assisted, Label-free, Non-invasive Approach for Somatic Reprogramming in Induced Pluripotent Stem Cell Colony Formation Detection and Prediction

During cellular reprogramming, the mesenchymal-to-epithelial transition is accompanied by changes in morphology, which occur prior to iPSC colony formation. The current approach for detecting morphological changes associated with reprogramming purely relies on human experiences, which involve intens...

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Detalles Bibliográficos
Autores principales: Fan, Ke, Zhang, Sheng, Zhang, Ying, Lu, Jun, Holcombe, Mike, Zhang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647349/
https://www.ncbi.nlm.nih.gov/pubmed/29044152
http://dx.doi.org/10.1038/s41598-017-13680-x