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LRRC25 Functions as an Inhibitor of NF-κB Signaling Pathway by Promoting p65/RelA for Autophagic Degradation

Nuclear factor κB (NF-κB) is a family of critical transcription factors that play a critical role in innate immune responses and inflammation, yet the molecular mechanisms responsible for its tight regulation is not fully understood. In this study, we identified LRRC25, a member of leucine-rich repe...

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Detalles Bibliográficos
Autores principales: Feng, Yanchun, Duan, Tianhao, Du, Yang, Jin, Shouheng, Wang, Mingjun, Cui, Jun, Wang, Rong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647368/
https://www.ncbi.nlm.nih.gov/pubmed/29044191
http://dx.doi.org/10.1038/s41598-017-12573-3