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LRRC25 Functions as an Inhibitor of NF-κB Signaling Pathway by Promoting p65/RelA for Autophagic Degradation
Nuclear factor κB (NF-κB) is a family of critical transcription factors that play a critical role in innate immune responses and inflammation, yet the molecular mechanisms responsible for its tight regulation is not fully understood. In this study, we identified LRRC25, a member of leucine-rich repe...
Autores principales: | Feng, Yanchun, Duan, Tianhao, Du, Yang, Jin, Shouheng, Wang, Mingjun, Cui, Jun, Wang, Rong-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647368/ https://www.ncbi.nlm.nih.gov/pubmed/29044191 http://dx.doi.org/10.1038/s41598-017-12573-3 |
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