Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro

Paclitaxel (PTX) is one of the drugs of choice in the treatment of breast and lung cancer. However, its severe side effects, including mielosuppression, cardiotoxicity and neurotoxicity, frequently cause treatment to be discontinued. Solid lipid nanoparticles (NPs) of glyceril tripalmitate (tripalmi...

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Detalles Bibliográficos
Autores principales: Leiva, María Carmen, Ortiz, Raúl, Contreras-Cáceres, Rafael, Perazzoli, Gloria, Mayevych, Iryna, López-Romero, Juan Manuel, Sarabia, Francisco, Baeyens, Jose Manuel, Melguizo, Consolación, Prados, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647375/
https://www.ncbi.nlm.nih.gov/pubmed/29044153
http://dx.doi.org/10.1038/s41598-017-13816-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647375/
https://www.ncbi.nlm.nih.gov/pubmed/29044153
http://dx.doi.org/10.1038/s41598-017-13816-z

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