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Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro
Paclitaxel (PTX) is one of the drugs of choice in the treatment of breast and lung cancer. However, its severe side effects, including mielosuppression, cardiotoxicity and neurotoxicity, frequently cause treatment to be discontinued. Solid lipid nanoparticles (NPs) of glyceril tripalmitate (tripalmi...
Autores principales: | Leiva, María Carmen, Ortiz, Raúl, Contreras-Cáceres, Rafael, Perazzoli, Gloria, Mayevych, Iryna, López-Romero, Juan Manuel, Sarabia, Francisco, Baeyens, Jose Manuel, Melguizo, Consolación, Prados, Jose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647375/ https://www.ncbi.nlm.nih.gov/pubmed/29044153 http://dx.doi.org/10.1038/s41598-017-13816-z |
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