Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels

Tetrameric coiled-coil structures are present in many ion channels, often adjacent to a calmodulin (CaM) binding site, although the relationship between the two is not completely understood. Here we examine the dynamic properties of the ABCD domain located in the intracellular C-terminus of tetramer...

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Detalles Bibliográficos
Autores principales: Alaimo, Alessandro, Nuñez, Eider, Aivar, Paloma, Fernández-Orth, Juncal, Gomis-Perez, Carolina, Bernardo-Seisdedos, Ganeko, Malo, Covadonga, Villarroel, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647379/
https://www.ncbi.nlm.nih.gov/pubmed/29044210
http://dx.doi.org/10.1038/s41598-017-13811-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647379/
https://www.ncbi.nlm.nih.gov/pubmed/29044210
http://dx.doi.org/10.1038/s41598-017-13811-4

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