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The neonicotinoid insecticide Clothianidin adversely affects immune signaling in a human cell line

Clothianidin is a widely used neonicotinoid insecticide, which is a potent agonist of the nicotinic acetylcholine receptor in insects. This neurotoxic compound has a negative impact on insect immunity, as it down-regulates the activation of the transcription factor NF-κB. Given the evolutionary cons...

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Detalles Bibliográficos
Autores principales: Di Prisco, Gennaro, Iannaccone, Marco, Ianniello, Flora, Ferrara, Rosalba, Caprio, Emilio, Pennacchio, Francesco, Capparelli, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647381/
https://www.ncbi.nlm.nih.gov/pubmed/29044138
http://dx.doi.org/10.1038/s41598-017-13171-z