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Rapid Generation and Detection of Biomimetic Oxygen Concentration Gradients In Vitro

Hypoxic regions exist within most solid tumors and often lead to altered cellular metabolism, metastasis, and drug resistance. Reliable generation and detection of biomimetic gaseous gradients in vitro is challenging due to low spatiotemporal resolution and poor longevity of gradients utilizing micr...

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Detalles Bibliográficos
Autores principales: Khan, Daud H., Roberts, Steven A., Cressman, John Robert, Agrawal, Nitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647399/
https://www.ncbi.nlm.nih.gov/pubmed/29044222
http://dx.doi.org/10.1038/s41598-017-13886-z