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Limits of aerobic metabolism in cancer cells

Cancer cells exhibit high rates of glycolysis and glutaminolysis. Glycolysis can provide energy and glutaminolysis can provide carbon for anaplerosis and reductive carboxylation to citrate. However, all these metabolic requirements could be in principle satisfied from glucose. Here we investigate wh...

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Detalles Bibliográficos
Autores principales: Fernandez-de-Cossio-Diaz, Jorge, Vazquez, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647437/
https://www.ncbi.nlm.nih.gov/pubmed/29044214
http://dx.doi.org/10.1038/s41598-017-14071-y