Evaluation of in vitro and in vivo therapeutic antitumor efficacy of transduction of polo-like kinase 1 and heat shock transcription factor 1 small interfering RNA

Mitotic progression is regulated by the phosphorylation of heat shock transcription factor 1 (HSF1) by polo-like kinase 1 (PLK1); however, this interaction is often deregulated in tumors. High expression levels of PLK1 and HSF1 have been observed in various types of human cancer. In the present stud...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Kikuchi, Takuto, Ozaki, Kei-Ichi, Onishi, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647550/
https://www.ncbi.nlm.nih.gov/pubmed/29067111
http://dx.doi.org/10.3892/etm.2017.5060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647550/
https://www.ncbi.nlm.nih.gov/pubmed/29067111
http://dx.doi.org/10.3892/etm.2017.5060

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