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A Randomized, Phase II Study of Preoperative plus Postoperative Imatinib in GIST: Evidence of Rapid Radiographic Response and Temporal Induction of Tumor Cell Apoptosis

Gastrointestinal stromal tumor (GIST) is the most common sarcoma arising in the gastrointestinal (GI) tract. Imatinib mesylate (imatinib) is efficacious in treating advanced and metastatic GIST. Patients undergoing resection of GIST realize a highly variable median disease-free survival (DFS). In th...

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Detalles Bibliográficos
Autores principales: McAuliffe, John C., Hunt, Kelly K., Lazar, Alexander J. F., Choi, Haesun, Qiao, Wei, Thall, Peter, Pollock, Raphael E., Benjamin, Robert S., Trent, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647649/
https://www.ncbi.nlm.nih.gov/pubmed/18953611
http://dx.doi.org/10.1245/s10434-008-0177-7