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Maintenance efficacy designs in psychiatry: Randomized discontinuation trials – enriched but not better

INTRODUCTION: Although classical randomized clinical trials (RCTs) are the gold standard for proof of drug efficacy, randomized discontinuation trials (RDTs), sometimes called “enriched” trials, are used increasingly, especially in psychiatric maintenance studies. METHODS: A narrative review of two...

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Detalles Bibliográficos
Autores principales: Ghaemi, S. N., Selker, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647671/
https://www.ncbi.nlm.nih.gov/pubmed/29082033
http://dx.doi.org/10.1017/cts.2017.2