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Maintenance efficacy designs in psychiatry: Randomized discontinuation trials – enriched but not better
INTRODUCTION: Although classical randomized clinical trials (RCTs) are the gold standard for proof of drug efficacy, randomized discontinuation trials (RDTs), sometimes called “enriched” trials, are used increasingly, especially in psychiatric maintenance studies. METHODS: A narrative review of two...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cambridge University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647671/ https://www.ncbi.nlm.nih.gov/pubmed/29082033 http://dx.doi.org/10.1017/cts.2017.2 |