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Role of blocking ADAM10 hydrolysis site on N-cadherin by single-chain antibody in ventricular remodeling

The present study aimed to investigate the roles of the hydrolytic process of N-cadherin by A disintegrin and metalloproteases 10 (ADAM10) in sustaining myocardial structure and integrity, and discuss the mechanisms of ventricular remodeling in dilated cardiomyopathy (DCM). Single chain variable fra...

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Detalles Bibliográficos
Autores principales: Li, Xiaoou, Huang, Wei, He, Bing, Zhou, Lirong, Huang, Xiaogang, Yao, Baozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647691/
https://www.ncbi.nlm.nih.gov/pubmed/29067106
http://dx.doi.org/10.3892/etm.2017.5057