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Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains

Using an aerobic oxidative coupling, different new imidazo[1,2-a]-N-heterocycles with gem-difluroroalkyl side chains have been prepared in fair yields by the reaction of gem-difluoroenones with aminopyridines, -pyrimidines and -pyridazines. Condensed heterocycles of this type play an important role...

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Detalles Bibliográficos
Autores principales: Hariss, Layal, Hadir, Kamal Bou, El-Masri, Mirvat, Roisnel, Thierry, Grée, René, Hachem, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647726/
https://www.ncbi.nlm.nih.gov/pubmed/29062431
http://dx.doi.org/10.3762/bjoc.13.208