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Prazosin during threat discrimination boosts memory of the safe stimulus

The α-1 adrenoreceptor antagonist prazosin has shown promise in the treatment of post-traumatic stress disorder (PTSD) symptoms, but its mechanisms are not well understood. Here we administered prazosin or placebo prior to threat conditioning (day 1) and tested subsequent extinction (day 2) and reex...

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Detalles Bibliográficos
Autores principales: Homan, Philipp, Lin, Qi, Murrough, James W., Soleimani, Laili, Bach, Dominik R., Clem, Roger L., Schiller, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647929/
https://www.ncbi.nlm.nih.gov/pubmed/29038221
http://dx.doi.org/10.1101/lm.045898.117